Cell Biology · Recruiting

Gut Microbiome Signatures in Type 2 Diabetes Remission

Dietary remission programmes work for some patients and not others, and clinicians have no way to predict who will respond.

Principal investigator: Dr. Lindiwe Dube

Gut Microbiome Signatures in Type 2 Diabetes Remission
Research
Programme

40+

Active programmes across clinical, agri and environmental science

60+

Partner institutions, hospitals and grower networks

180

Peer-reviewed publications and field reports to date

Objectives

  • Profile the gut microbiome of 800 participants entering remission programmes
  • Identify predictive taxa and metabolic pathways
  • Prototype a clinic-ready stratification test

Methodology

  1. 1Prospective cohort
  2. 2Shotgun metagenomics
  3. 3Continuous glucose monitoring
  4. 4Machine-learning stratification

Partners

  • Diabetes Association
  • Regional Nutrition Institute

Publications

    Connected

    Laboratories and services behind this study

    Research lifecycle

    From a question worth asking to a result people can use

    01

    Scoping

    Define the decision, the endpoint and the population or field site with our partners.

    02

    Protocol & ethics

    Pre-registered protocol, ethics or biosafety approval and consent frameworks.

    03

    Execution

    Accredited laboratory and field workflows with monitored data capture.

    04

    Translation

    Peer-reviewed publication, regulatory dossiers and hand-off to service teams.

    Partner with us

    Collaborate on Gut Microbiome Signatures in Type 2 Diabetes Remission

    Bring us a study, a sample set or a field problem. We scope feasibility, ethics and timelines within one working week.

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    Publications & data access

    Request pre-prints, anonymised datasets or replication protocols from any completed programme.